Recurrence and Management Challenges of Upper Eyelid Pilomatrixoma: A Rare Case Study with Atypical Presentation

Pilomatrixoma is a benign tumor of the hair matrix cells and is usually confused with other entities since there are nonspecific findings. Most of the patients are young individuals, and involvement is usually in the head and neck region; however, rarely, involvement in the periorbital area has been reported. We present the recurrent case of pilomatrixoma in a 37-year-old male upper eyelid, as well as diagnostic and treatment difficulties that are commonly found in these tumors. The tumor was initially excised under local anesthesia. After three months, it recurred, which was further confirmed on histopathology as pilomatrixoma due to its characteristic features of basaloid cells and ghost cell formation. A good point here is that a recurrent tumor following good initial removal points to the necessity for very careful follow-up or, perhaps, more aggressive initial surgery. This underlines the fact that pilomatrixoma can present with a varied clinical spectrum; hence, histopathological confirmation is necessary for case definition. Pilomatrixoma, in some way, recalls the fact that, though the treatment is adequate at first, a chance of recurrence is probable and, thus, contributes to the body of experience in managing this rare disease.

Authors

Institutions

Publication Details

Journal
AL-Kindy College Medical Journal
Published
2025-04-01
DOI
https://doi.org/10.47723/ph609z67
Primary Topic
Cancer and Skin Lesions
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Recurrence and Management Challenges of Upper Eyelid Pilomatrixoma: A Rare Case Study with Atypical Presentation

Najah K. Mohammad
AL-Kindy College Medical Journal
Cancer and Skin Lesions
article

Recurrence and Management Challenges of Upper Eyelid Pilomatrixoma: A Rare Case Study with Atypical Presentation

Najah K. Mohammad
article en

Abstract

Pilomatrixoma is a benign tumor of the hair matrix cells and is usually confused with other entities since there are nonspecific findings. Most of the patients are young individuals, and involvement is usually in the head and neck region; however, rarely, involvement in the periorbital area has been reported. We present the recurrent case of pilomatrixoma in a 37-year-old male upper eyelid, as well as diagnostic and treatment difficulties that are commonly found in these tumors. The tumor was initially excised under local anesthesia. After three months, it recurred, which was further confirmed on histopathology as pilomatrixoma due to its characteristic features of basaloid cells and ghost cell formation. A good point here is that a recurrent tumor following good initial removal points to the necessity for very careful follow-up or, perhaps, more aggressive initial surgery. This underlines the fact that pilomatrixoma can present with a varied clinical spectrum; hence, histopathological confirmation is necessary for case definition. Pilomatrixoma, in some way, recalls the fact that, though the treatment is adequate at first, a chance of recurrence is probable and, thus, contributes to the body of experience in managing this rare disease.

AL-Kindy College Medical JournalVol. 21(1)
University of Baghdad (IQ)
Openalex Percentile: Top 87%
Cancer and Skin Lesions
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.