Melatonin as a Possible Stimulus to Unmask an Oxytocin-Deficient State in Hypopituitarism and Hypothalamic Damage
The reduced OXT response after MEL in HHD supports the existence of an impaired OXT response at least in a subset of patients with HHD. The associations between OXT changes and psychopathology suggest its role in mood and QoL. These findings support further investigation into MEL's role as a diagnostic tool to address OXT-D.
Authors
- Eulàlia Urgell (ORCID: https://orcid.org/0000-0003-3519-1022)
- Alicia Santos (ORCID: https://orcid.org/0000-0002-2179-6189)
- Nimmy Varghese (ORCID: https://orcid.org/0000-0001-8598-0535)
- Anna Aulinas (ORCID: https://orcid.org/0000-0002-1205-7114)
- Cihan Atila (ORCID: https://orcid.org/0000-0002-5442-7304)
- Susan M. Webb (ORCID: https://orcid.org/0000-0001-7052-6436)
- Anne Eckert (ORCID: https://orcid.org/0000-0002-9341-3669)
- Queralt Asla (ORCID: https://orcid.org/0000-0001-6049-8048)
- Mirjam Christ‐Crain (ORCID: https://orcid.org/0000-0002-6336-0965)
- Maite Garrido
- Betina Biagetti (ORCID: https://orcid.org/0000-0002-8837-4343)
- Franziska Plessow (ORCID: https://orcid.org/0000-0002-9721-7817)
- Elizabeth A. Lawson (ORCID: https://orcid.org/0000-0001-8619-3349)
- Sílvia Terzan
Institutions
- Universitat de Vic - Universitat Central de Catalunya (ES)
- Universitat Autònoma de Barcelona (ES)
- Harvard University (US)
- University of Basel (CH)
- Instituto de Salud Carlos III (ES)
- Hospital de Sant Pau (ES)
- University Hospital of Basel (CH)
- Massachusetts General Hospital (US)
- Centre for Biomedical Network Research on Rare Diseases (ES)
- Vall d'Hebron Hospital Universitari (ES)
- Department of Biomedicine Basel (CH)
- Iberoamerican Cochrane Centre (ES)
- Instituto de Investigación de Enfermedades Raras (ES)
- Universitäre Psychiatrische Kliniken Basel (CH)
Publication Details
- Journal
- The Journal of Clinical Endocrinology & Metabolism
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1210/clinem/dgaf201
- Citations
- 5
- Primary Topic
- Neuroendocrine regulation and behavior
- Type
- article
- Field-Weighted Citation Impact
- 12.19
Funders
- Instituto de Salud Carlos III
- European Regional Development Fund