Effects of the augmentation with quetiapine or olanzapine on the metabolism of duloxetine: a retrospective analysis
Our findings indicate that the combination of duloxetine and olanzapine or quetiapine is - from a pharmacokinetic view - a safe treatment option. TDM should be applied in case of co-medications to enhance therapeutic effectiveness and patients' safety.
Authors
- Christoph Hiemke (ORCID: https://orcid.org/0000-0003-2820-8738)
- Arnim Johannes Gaebler (ORCID: https://orcid.org/0000-0002-8816-3415)
- Irene Neuner (ORCID: https://orcid.org/0000-0002-5164-8873)
- Michael Paulzen (ORCID: https://orcid.org/0000-0003-4198-5160)
- Georgios Schoretsanitis (ORCID: https://orcid.org/0000-0002-3851-4117)
- Ekkehard Haen (ORCID: https://orcid.org/0000-0003-4430-4148)
- Nele Römer
Institutions
- Northwell Health (US)
- Hofstra University (US)
- Johannes Gutenberg University Mainz (DE)
- University of Zurich (CH)
- Centre for Mental Health (GB)
- University Medical Center of the Johannes Gutenberg University Mainz (DE)
- University Hospital of Zurich (CH)
- Brain (Germany) (DE)
- Universitätsklinikum Aachen (DE)
- Zucker Hillside Hospital (US)
- University of Regensburg (DE)
- RWTH Aachen University (DE)
Publication Details
- Journal
- Expert Review of Clinical Pharmacology
- Published
- 2025-04-04
- DOI
- https://doi.org/10.1080/17512433.2025.2486998
- Primary Topic
- Treatment of Major Depression
- Type
- article
- Field-Weighted Citation Impact
- 0.00