IMMUNE RESPONSE OF CULTURED MONOCYTES OF ATHEROSCLEROTIC PATIENTS RECEIVING STATIN THERAPY.
Thus, the study demonstrated the significant decrease of inflammatory cytokines secretion by cultured monocytes of patients with coronary atherosclerosis receiving statin therapy. The most prominent effect was observed in rosuvastatin recipients. The reduction of the TNF-α and IL-1β secretion by monocytes correlated with low levels of total cholesterol and LDL.
Authors
- Natalia V. Elizova
- Tatiana V. Kirichenko (ORCID: https://orcid.org/0000-0002-2899-9202)
- Maria M. Lukina (ORCID: https://orcid.org/0000-0003-1374-8571)
- Т. Б. Андрущишина (ORCID: https://orcid.org/0000-0001-7940-4443)
- А. А. Маркин (ORCID: https://orcid.org/0000-0002-2402-6622)
- Yuliya V. Markina (ORCID: https://orcid.org/0000-0002-3781-6340)
- Irina Y. Yudina (ORCID: https://orcid.org/0000-0002-4138-6371)
Institutions
- Sechenov University (RU)
- Moscow State University of Civil Engineering (RU)
- National Medical Research Center of Cardiology (RU)
Publication Details
- Journal
- PubMed
- Published
- 2025-01-01
- Primary Topic
- Atherosclerosis and Cardiovascular Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00