[Dexmedetomidine attenuates heat stress-induced oncosis in human skeletal muscle cells by activating the Nrf2/Ho-1 pathway].
DEX mitigates HS-induced HSKMC oncosis by activating the Nrf2/HO-1 pathway to relieve oxidative stress, mitochondrial dysfunction, and inflammatory responses.
Authors
- Yi‐Qing Jia
- Shuyuan Liu (ORCID: https://orcid.org/0000-0003-1709-0025)
- Handing Mao (ORCID: https://orcid.org/0000-0003-1603-3205)
- Chengcheng Li (ORCID: https://orcid.org/0000-0002-4843-5404)
- Liu Yang (ORCID: https://orcid.org/0000-0001-9729-7194)
- Yi Shan (ORCID: https://orcid.org/0000-0002-6799-6266)
Institutions
- South China University of Technology (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-03-20
- DOI
- https://doi.org/10.12122/j.issn.1673-4254.2025.03.18
- Primary Topic
- Hydrogen's biological and therapeutic effects
- Type
- article