Adult Onset Retinoblastoma: Two Rare Case Reports.

Retinoblastoma in adult is one of rarer findings and always causing a diagnostic dilemma. Our two reported cases were 20 and 40 years old and both were male. Both cases presented with unilateral vision loss and without any positive family history. Clinical examination of the first case revealed whitish mass in hazy vitreous along with neovascularization of iris and raised intraocular pressure. In second case, dilated fundus examination showed elevated whitish retinal mass with feeder vessel. Both cases were diagnosed mostly clinically and surgically managed by enucleation with long optic nerve. Histopathology confirmed the diagnosis of retinoblastoma of adult onset and was not associated with histopathological high risk factors. Physician's high suspicion is needed to rule out retinoblastoma in any amelanotic retinal lesions in adult to save life as retinoblastoma is a devastating disease.

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PubMed
Published
2025-04-01
Primary Topic
Ocular Oncology and Treatments
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article
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article

Adult Onset Retinoblastoma: Two Rare Case Reports.

Somnath Roy, Murtuza Nuruddin, F Huque
PubMed
Ocular Oncology and Treatments
article

Adult Onset Retinoblastoma: Two Rare Case Reports.

Somnath Roy, Murtuza Nuruddin, F Huque
article en

Abstract

Retinoblastoma in adult is one of rarer findings and always causing a diagnostic dilemma. Our two reported cases were 20 and 40 years old and both were male. Both cases presented with unilateral vision loss and without any positive family history. Clinical examination of the first case revealed whitish mass in hazy vitreous along with neovascularization of iris and raised intraocular pressure. In second case, dilated fundus examination showed elevated whitish retinal mass with feeder vessel. Both cases were diagnosed mostly clinically and surgically managed by enucleation with long optic nerve. Histopathology confirmed the diagnosis of retinoblastoma of adult onset and was not associated with histopathological high risk factors. Physician's high suspicion is needed to rule out retinoblastoma in any amelanotic retinal lesions in adult to save life as retinoblastoma is a devastating disease.

PubMedVol. 34(2)
Chattogram Veterinary and Animal Sciences University (BD)
Openalex Percentile: Top 89%
Ocular Oncology and Treatments
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