[High expression of hexokinase 2 promotes proliferation, migration and invasion of colorectal cancer cells by activating the JAK/STAT pathway and regulating tumor immune microenvironment].

HK2 is upregulated in CRC to promote tumor cell proliferation, migration and invasion possibly by activating the JAK-STAT signaling pathway and modulating tumor immune microenvironment.

Authors

Zhiyong Shen (ORCID: https://orcid.org/0000-0003-4950-2434)
Shunjie Qing

Institutions

Nanfang Hospital (CN)
Southern Medical University (CN)

Publication Details

Journal: PubMed
Published: 2025-03-20
DOI: https://doi.org/10.12122/j.issn.1673-4254.2025.03.12
Primary Topic: Cancer, Hypoxia, and Metabolism
Type: article

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article

[High expression of hexokinase 2 promotes proliferation, migration and invasion of colorectal cancer cells by activating the JAK/STAT pathway and regulating tumor immune microenvironment].

Zhiyong Shen, Shunjie Qing

Mar 20, 2025

PubMed

Cancer, Hypoxia, and Metabolism

article

[High expression of hexokinase 2 promotes proliferation, migration and invasion of colorectal cancer cells by activating the JAK/STAT pathway and regulating tumor immune microenvironment].

Zhiyong Shen, Shunjie Qing

March 20, 2025article en

Abstract

HK2 is upregulated in CRC to promote tumor cell proliferation, migration and invasion possibly by activating the JAK-STAT signaling pathway and modulating tumor immune microenvironment.

PubMedVol. 45(3)

Nanfang Hospital (CN), Southern Medical University (CN)

Cancer, Hypoxia, and Metabolism

DOI Source OpenAlex

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[High expression of hexokinase 2 promotes proliferation, migration and invasion of colorectal cancer cells by activating the JAK/STAT pathway and regulating tumor immune microenvironment]. — Zhiyong Shen, Shunjie Qing · PubMed (2025) | TGRS Research Map | TGRS