Comparative assessment of artificial intelligence chatbots' performance in responding to healthcare professionals' and caregivers' questions about Dravet syndrome

Artificial intelligence chatbots have the potential to improve access to medical information, including on conditions like Dravet syndrome, but the quality of this information is still unclear. In this study, ChatGPT 3.5 and Perplexity correctly answered most questions from healthcare professionals and caregivers, with ChatGPT 3.5 performing better for caregivers. Treatment-related questions had the most incorrect answers, particularly those from healthcare professionals. Both chatbots demonstrated the ability to correct previous incorrect responses, particularly Perplexity. Both chatbots produced text requiring advanced reading skills. Further improvements are needed to make the text easier to understand and address difficult medical topics.