Associations of moderate alcohol intake with cerebrospinal fluid biomarkers of Alzheimer’s disease: data from the ALBION study
Light-to-moderate alcohol intake was associated with higher Aβ deposition in middle-aged individuals without dementia, compared to abstinence. High adherence to the MADP, which indicates low-to-moderate red wine consumption distributing over the week with meals, was associated with a higher Aβ and Tau/Aβ and PTau/Aβ positivity. Therefore, the management of alcohol consumption may help improve AD outcomes even at the preclinical stage.
Authors
- Archontoula Drouka (ORCID: https://orcid.org/0000-0002-7578-1863)
- Dora Brikou
- Yian Gu (ORCID: https://orcid.org/0000-0002-4297-1548)
- Eva Ntanasi (ORCID: https://orcid.org/0000-0001-9311-0994)
- Mary Yannakoulia (ORCID: https://orcid.org/0000-0003-2171-7337)
- Stylianos Chatzipanagiotou (ORCID: https://orcid.org/0000-0002-1251-8355)
- Eirini Mamalaki (ORCID: https://orcid.org/0000-0002-5714-3032)
- Nikolaos Scarmeas (ORCID: https://orcid.org/0000-0001-6453-8908)
- Klairi-Despoina Ntetsika
Institutions
- National and Kapodistrian University of Athens (GR)
- Harokopio University of Athens (GR)
- Eginition Hospital (GR)
- Columbia University (US)
Publication Details
- Journal
- European Journal of Nutrition
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1007/s00394-025-03651-8
- Citations
- 7
- Primary Topic
- Alcohol Consumption and Health Effects
- Type
- article
- Field-Weighted Citation Impact
- 10.30
Funders
- Harokopio University