[Expert consensus on airway complications after lung transplantation].

Lung transplantation is the only effective treatment for end-stage pulmonary disease. As surgical techniques and post-operative management protocols have been optimised, the number of lung transplantations has steadily increased worldwide. Airway complications (AC), which include airway stenosis, tracheobronchomalacia, ischemic necrosis, and anastomotic leaks, are one of the most common complications following lung transplantation, with an overall incidence ranging from 15% to 20%. These complications have a significant impact on the quality of life and survival rate of transplant recipients, with airway stenosis being the most common. In lung transplant recipients, AC can affect both large and small airways, with the majority of large airway complications occurring within the first year after surgery. This consensus focuses specifically on AC of large airways. It is widely recognized that impaired bronchial blood supply is a common underlying cause of AC due to a variety of factors. The post-transplant management of AC, particularly the technical requirements for specialized interventional procedures, remains a major challenge. Currently, there is no standardized diagnostic and therapeutic approach within the country. This consensus aims to unify and propose guidelines on the diagnosis, treatment options, interventional strategies, methodologies, and key considerations for the management of AC after lung transplantation, with the hope of improving patient outcomes and serving as a reference for practitioners in the field.

Publication Details

Journal
PubMed
Published
2025-04-12
DOI
https://doi.org/10.3760/cma.j.cn112147-20240814-00485
Primary Topic
Transplantation: Methods and Outcomes
Type
article
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

[Expert consensus on airway complications after lung transplantation].

PubMed
Transplantation: Methods and Outcomes
article

[Expert consensus on airway complications after lung transplantation].

article en

Abstract

Lung transplantation is the only effective treatment for end-stage pulmonary disease. As surgical techniques and post-operative management protocols have been optimised, the number of lung transplantations has steadily increased worldwide. Airway complications (AC), which include airway stenosis, tracheobronchomalacia, ischemic necrosis, and anastomotic leaks, are one of the most common complications following lung transplantation, with an overall incidence ranging from 15% to 20%. These complications have a significant impact on the quality of life and survival rate of transplant recipients, with airway stenosis being the most common. In lung transplant recipients, AC can affect both large and small airways, with the majority of large airway complications occurring within the first year after surgery. This consensus focuses specifically on AC of large airways. It is widely recognized that impaired bronchial blood supply is a common underlying cause of AC due to a variety of factors. The post-transplant management of AC, particularly the technical requirements for specialized interventional procedures, remains a major challenge. Currently, there is no standardized diagnostic and therapeutic approach within the country. This consensus aims to unify and propose guidelines on the diagnosis, treatment options, interventional strategies, methodologies, and key considerations for the management of AC after lung transplantation, with the hope of improving patient outcomes and serving as a reference for practitioners in the field.

PubMedVol. 48(4)
Transplantation: Methods and Outcomes
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.