Effect of Intra-Operative Topical 5-Fluorouracil Post-Functional Endoscopic Sinus Surgery: A Randomized Controlled Trial.

Adhesions are less common in the early postoperative period in individuals who underwent FESS with or without polypectomy when 5-FU is administered topically. There is also an improvement in smell perception with a reduction of mucosal edema, crusting, polypoidal change and nasal discharge enabling better healing.

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Publication Details

Journal
PubMed
Published
2025-01-01
DOI
https://doi.org/10.22038/ijorl.2025.80571.3709
Primary Topic
Head and Neck Surgical Oncology
Type
article
Field-Weighted Citation Impact
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article

Effect of Intra-Operative Topical 5-Fluorouracil Post-Functional Endoscopic Sinus Surgery: A Randomized Controlled Trial.

Urvashi Singh, Lekhaa Mohanraj, Somu Lakshmanan
1 links
PubMed
Head and Neck Surgical Oncology
article

Effect of Intra-Operative Topical 5-Fluorouracil Post-Functional Endoscopic Sinus Surgery: A Randomized Controlled Trial.

Urvashi Singh, Lekhaa Mohanraj, Somu Lakshmanan
article en

Abstract

Adhesions are less common in the early postoperative period in individuals who underwent FESS with or without polypectomy when 5-FU is administered topically. There is also an improvement in smell perception with a reduction of mucosal edema, crusting, polypoidal change and nasal discharge enabling better healing.

PubMedVol. 37(2)
Apollo Hospitals (IN)
Openalex Percentile: Top 89%
Head and Neck Surgical Oncology
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