ISCEV standard full-field ERG reference limits from 407 healthy subjects, derived from transference and validation of reference data between electrode types and centres
ISCEV standard silver thread ERG data were consistent across the two centres, allowing transference of reference data. Reference data recorded with gold foil electrodes can be transformed for inclusion in a silver thread ERG reference range. The study highlights methods of pooling multiple sources of reference data into a larger, more robust sample, pertinent to standardization, clinical management, and multi-centre studies. These reference data could be adopted by other centres or combined with other datasets, following suitable verification.
Authors
- Shaun M. Leo (ORCID: https://orcid.org/0000-0003-2396-872X)
- Antonio Calcagni (ORCID: https://orcid.org/0000-0002-1446-3546)
- Isabelle Chow
- Rebecca Baker (ORCID: https://orcid.org/0000-0001-9436-7329)
- M. Neveu (ORCID: https://orcid.org/0000-0002-3859-0865)
- Anthony G. Robson (ORCID: https://orcid.org/0000-0002-8391-6123)
- Xiaofan Jiang (ORCID: https://orcid.org/0000-0002-6480-0299)
- Omar A. Mahroo (ORCID: https://orcid.org/0000-0003-1254-0832)
- Christopher Joseph Hammond (ORCID: https://orcid.org/0000-0002-3227-2620)
- Anne Georgiou
- William I N Clowes
Institutions
- St Thomas' Hospital (GB)
- Moorfields Eye Hospital NHS Foundation Trust (GB)
- Anthony Nolan (GB)
- University College London (GB)
Publication Details
- Journal
- Documenta Ophthalmologica
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1007/s10633-025-10009-2
- Citations
- 1
- Primary Topic
- Retinal Development and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- Wellcome Trust
- National Institute for Health Research Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology