Impact of Cold Ischemic Time on Nucleic Acid Quality in Cytology Samples for Cancer Gene Analysis
This study's findings suggest that DNA extracted from cytology samples is highly stable, while RNA is affected by cold ischemic time. Thus, prompt fixation after collection is necessary to maintain RNA quality.
Authors
- Jun Akiba (ORCID: https://orcid.org/0000-0003-2657-8604)
- Hideyuki Abe (ORCID: https://orcid.org/0000-0003-0704-8413)
- Akihiko Kawahara (ORCID: https://orcid.org/0000-0002-4081-2519)
- Hironori Kusano (ORCID: https://orcid.org/0000-0002-9911-2007)
- Takato KUMAGAE
- Reiko Makino
Institutions
- Kurume University (JP)
- Kurume University Hospital (JP)
Publication Details
- Journal
- Cytopathology
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1111/cyt.13491
- Primary Topic
- Molecular Biology Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00