Association Between Educational Attainment and Chronic Pain: A Mediation Mendelian Randomization Study
Genetically predicted higher educational attainment reduces multisite chronic pain risk, partially mediated by body mass index (17.1%), smoking (23.6%), and depression (9.2%), highlighting education's protective role and its potential in chronic pain prevention strategies.
Authors
- H. Wang (ORCID: https://orcid.org/0000-0003-3468-9312)
- Shijie Xu (ORCID: https://orcid.org/0000-0001-6983-2508)
- Mingjuan Liu (ORCID: https://orcid.org/0000-0002-3040-0561)
- Hongbo Li
Institutions
- First Hospital of Jiaxing (CN)
Publication Details
- Journal
- Journal of Pain Research
- Published
- 2025-04-01
- DOI
- https://doi.org/10.2147/jpr.s515921
- Citations
- 4
- Primary Topic
- Genetics and Physical Performance
- Type
- article
- Field-Weighted Citation Impact
- 7.27