Palladium-catalyzed reductive cross-coupling reaction of carboxylic acids with thiols: an alternative strategy to access thioesters
A practical and alternative approach to access thioesters is presented, utilizing readily available starting precursors such as carboxylic acids and thiols <i>via</i> direct reductive C-S cross-coupling reactions under palladium catalysis. The present protocol features good atom economy, excellent yields, wide functional group tolerance, broad substrate scope, operational simplicity, and mild reaction conditions with no additional steps.
Authors
- Ying Chang (ORCID: https://orcid.org/0000-0003-4016-6200)
- Satpal Singh Badsara (ORCID: https://orcid.org/0000-0002-9839-5113)
- Chin‐Fa Lee (ORCID: https://orcid.org/0000-0003-0735-5691)
- Rekha Bai (ORCID: https://orcid.org/0000-0001-9080-0754)
- Indrajit Karmakar (ORCID: https://orcid.org/0000-0002-2713-8080)
- Sunwoo Lee (ORCID: https://orcid.org/0000-0001-5079-3860)
- Yang-Ting Hsia
Institutions
- Chonnam National University (KR)
- National Chung Hsing University (TW)
- Banaras Hindu University (IN)
Publication Details
- Journal
- Organic & Biomolecular Chemistry
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5ob00151j
- Citations
- 4
- Primary Topic
- Sulfur-Based Synthesis Techniques
- Type
- article
- Field-Weighted Citation Impact
- 3.74