Comparison of the Novel Thrombolytic Constitutively Active ADAMTS13 With Clinical Thrombolytics in a Murine Stroke Model
These findings demonstrate an overall suggestion that caADAMTS13 has improved thrombolytic efficacy, compared with current stroke treatments, against platelet-rich thrombi, for which there is currently an unmet clinical need.
Authors
- Ben Dickie (ORCID: https://orcid.org/0000-0001-5018-2111)
- Stuart M. Allan (ORCID: https://orcid.org/0000-0001-9646-4456)
- Graham Coutts (ORCID: https://orcid.org/0000-0002-5865-9495)
- Lucy Roberts (ORCID: https://orcid.org/0000-0001-6349-5117)
- Craig J. Smith (ORCID: https://orcid.org/0000-0002-9078-9919)
- Kieron South (ORCID: https://orcid.org/0000-0002-9141-3438)
Institutions
- Manchester Academic Health Science Centre (GB)
- Salford Royal NHS Foundation Trust (GB)
- University of Manchester (GB)
Publication Details
- Journal
- Stroke
- Published
- 2025-04-02
- DOI
- https://doi.org/10.1161/strokeaha.125.050848
- Citations
- 4
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 5.42