Endothelial insulin-like growth factor-1 signalling regulates vascular barrier function and atherogenesis
Endothelial IGF-1 signalling modulates both para- and transcellular vascular barrier function. Beyond reducing atherosclerosis, this could have relevance to many diseases associated with abnormal vascular permeability.
Authors
- Hema Viswambharan (ORCID: https://orcid.org/0000-0002-7616-5026)
- Andrew MN Walker (ORCID: https://orcid.org/0000-0003-0380-7283)
- Helen Imrie
- Piruthivi Sukumar (ORCID: https://orcid.org/0000-0002-3294-989X)
- Mark T. Kearney (ORCID: https://orcid.org/0000-0002-9376-8814)
- Katherine S. Bridge (ORCID: https://orcid.org/0000-0003-1516-1459)
- Alexander-Francisco Bruns (ORCID: https://orcid.org/0000-0002-6970-4036)
- Nadira Yuldasheva (ORCID: https://orcid.org/0000-0001-6213-6358)
- David J. Beech (ORCID: https://orcid.org/0000-0002-7683-9422)
- Victoria Palin (ORCID: https://orcid.org/0000-0002-0851-8619)
- Chew W. Cheng
- Natalie J Haywood (ORCID: https://orcid.org/0000-0002-8762-7257)
- Lauren Eades
- Nele Warmke (ORCID: https://orcid.org/0000-0001-8037-2186)
- Anna Skromna (ORCID: https://orcid.org/0000-0002-4937-8675)
- Michael Drozd (ORCID: https://orcid.org/0000-0003-0255-4624)
- Stacey Galloway
- Richard M. Cubbon (ORCID: https://orcid.org/0000-0001-7844-3600)
- Stephen G. Wheatcroft (ORCID: https://orcid.org/0000-0002-0512-3275)
- Kathryn J Griffin (ORCID: https://orcid.org/0000-0002-3154-3273)
- Nicole T. Watt (ORCID: https://orcid.org/0000-0002-7429-7367)
- Natallia Makava
- Azhar Maqbool
Institutions
- University of Leeds (GB)
Publication Details
- Journal
- Cardiovascular Research
- Published
- 2025-04-02
- DOI
- https://doi.org/10.1093/cvr/cvaf055
- Citations
- 5
- Primary Topic
- Hippo pathway signaling and YAP/TAZ
- Type
- article
- Field-Weighted Citation Impact
- 5.76
Funders
- Biotechnology and Biological Sciences Research Council