Splicing factor PTBP1 promotes hepatocarcinogenesis via oncogenic splice-switching of MAPT
PTBP1-guided AS of the <i>MAPT</i> gene enhances tumorigenicity in HCC through activation of the MAPK/ERK pathways.
Authors
- Meiqi Li
- Min Deng (ORCID: https://orcid.org/0000-0003-1987-9775)
- Aiyun Luo (ORCID: https://orcid.org/0000-0001-9880-8259)
- Kai Du (ORCID: https://orcid.org/0000-0003-4598-2522)
- Yongfeng Shang (ORCID: https://orcid.org/0000-0001-5050-7625)
- Guoping Zhang (ORCID: https://orcid.org/0000-0002-9042-2607)
- Weixiong Zheng (ORCID: https://orcid.org/0000-0003-1372-4123)
- Lijun Pei
Institutions
- Guangzhou Medical University Cancer Hospital (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics
- Published
- 2025-01-01
- DOI
- https://doi.org/10.32604/or.2025.060958
- Citations
- 1
- Primary Topic
- RNA Research and Splicing
- Type
- article
- Field-Weighted Citation Impact
- 0.81