The Relationship Between Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio in Psoriasis Curative Effect Treated with Apremilast: A Retrospective Analysis

In this study, the changes of neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) in patients with psoriasis were retrospectively analyzed based on the treatment of apremilast. By screening patients with psoriasis before and after treatment with apremilast, relevant blood routine indicators were collected, and NLR and PLR were calculated. The results showed that both NLR and PLR were significantly reduced after treatment with apremilast. This suggests that the inflammatory response is improved in patients with psoriasis and that apremilast may have an inhibitory effect on white blood cell platelet activation. These results suggest that NLR and PLR may be useful indicators to evaluate the condition of psoriasis and the therapeutic effect of apremilast. This provides a new reference index and treatment strategy for the clinic and has positive practical guiding significance for the prevention and treatment of psoriasis.

Authors

Institutions

Publication Details

Journal
Dermatological Health
Published
2025-04-02
DOI
https://doi.org/10.26689/dh.v3i1.10021
Primary Topic
Inflammatory Biomarkers in Disease Prognosis
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

The Relationship Between Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio in Psoriasis Curative Effect Treated with Apremilast: A Retrospective Analysis

Sang Hoon Han, Ting Zhou, Faqing Huang
Dermatological Health
Inflammatory Biomarkers in Disease Prognosis
article

The Relationship Between Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio in Psoriasis Curative Effect Treated with Apremilast: A Retrospective Analysis

Sang Hoon Han, Ting Zhou, Faqing Huang
article en

Abstract

In this study, the changes of neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) in patients with psoriasis were retrospectively analyzed based on the treatment of apremilast. By screening patients with psoriasis before and after treatment with apremilast, relevant blood routine indicators were collected, and NLR and PLR were calculated. The results showed that both NLR and PLR were significantly reduced after treatment with apremilast. This suggests that the inflammatory response is improved in patients with psoriasis and that apremilast may have an inhibitory effect on white blood cell platelet activation. These results suggest that NLR and PLR may be useful indicators to evaluate the condition of psoriasis and the therapeutic effect of apremilast. This provides a new reference index and treatment strategy for the clinic and has positive practical guiding significance for the prevention and treatment of psoriasis.

Dermatological HealthVol. 3(1)
First People's Hospital of Jingzhou (CN)
Openalex Percentile: Top 91%
Inflammatory Biomarkers in Disease Prognosis
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.