Safety, efficacy and timing of antithrombotic therapy in emergency stenting of acute stroke patients with tandem lesions, German multicenter data-analysis

Only a minority of the examined GSR patients with tandem lesions had an effective APT during the periinterventional phase up to day 1. Early postinterventional DAPT significantly increased the rate of good clinical outcome and reduced the rate of occlusive stent thrombosis without increasing risks of symptomatic hemorrhage. The apparent lack of standards and moderate rates of good clinical outcomes shows room for improvement and the necessity of further studies.

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Publication Details

Journal
Frontiers in Neurology
Published
2025-04-02
DOI
https://doi.org/10.3389/fneur.2025.1554691
Citations
2
Primary Topic
Acute Ischemic Stroke Management
Type
article
Field-Weighted Citation Impact
2.71
Controls
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article

Safety, efficacy and timing of antithrombotic therapy in emergency stenting of acute stroke patients with tandem lesions, German multicenter data-analysis

Waltraud Pfeilschifter, Christian Grefkes, Christophe Théo Arendt, Leonhard Mann et al.
2 citations
Frontiers in Neurology
Acute Ischemic Stroke Management
2.71
article

Safety, efficacy and timing of antithrombotic therapy in emergency stenting of acute stroke patients with tandem lesions, German multicenter data-analysis

Waltraud Pfeilschifter, Christian Grefkes, Christophe Théo Arendt, Leonhard Mann, Joachim Berkefeld, Felix J. Bode, Simon Stahn, Ferdinand O. Bohmann, John W. Schaefer, Fee Christiane Keil, Elke Hattingen, Patrick Samp, Marios‐Nikos Psychogios, Lukas Bersch
article en
2 citations

Abstract

Only a minority of the examined GSR patients with tandem lesions had an effective APT during the periinterventional phase up to day 1. Early postinterventional DAPT significantly increased the rate of good clinical outcome and reduced the rate of occlusive stent thrombosis without increasing risks of symptomatic hemorrhage. The apparent lack of standards and moderate rates of good clinical outcomes shows room for improvement and the necessity of further studies.

Frontiers in NeurologyVol. 16
Goethe University Frankfurt (DE), University Hospital Bonn (DE), University Hospital of Basel (CH), Klinikum Lüneburg (DE), University Hospital Frankfurt (DE), Krankenhaus Nordwest (DE)
Openalex Percentile: Top 11%
Acute Ischemic Stroke Management
2.71
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Safety, efficacy and timing of antithrombotic therapy in emergency stenting of acute stroke patients with tandem lesions, German multicenter data-analysis — Waltraud Pfeilschifter, Christian Grefkes, et al. · Frontiers in Neurology (2025) | TGRS Research Map | TGRS