Exosomal miR-302b as a novel strategy for reversing cellular senescence and promoting healthy aging
The study by Bi <i>et al</i>. (2025) presents "Senoreverse", an innovative strategy that utilizes exosomal miR-302b to restore the proliferative capacity of senescent cells (SnCs), thus extending lifespan and enhancing cognitive and physical function in aging mice without the risk of tumorigenicity.
Authors
- Consuelo Borrás (ORCID: https://orcid.org/0000-0003-4606-1792)
Institutions
- Hospital Clínico Universitario de Valencia (ES)
- INCLIVA Health Research Institute (ES)
Publication Details
- Journal
- Extracellular Vesicles and Circulating Nucleic Acids
- Published
- 2025-04-02
- DOI
- https://doi.org/10.20517/evcna.2025.24
- Primary Topic
- Telomeres, Telomerase, and Senescence
- Type
- article
- Field-Weighted Citation Impact
- 0.00