<b>Expression profiles of the Tau-associated genes <i>GSk3β</i>, <i>CAPN1</i>, and <i>CDK5R1</i> in the brain cortex of aged female cynomolgus monkeys with cognitive impairment</b>
Our results add weight to the utility of cynomolgus macaques as a valid spontaneous model in translational preclinical research involving studies of the effect of aging on the formation of hyperphosphorylated tau protein, which causes AD-related lesions in the brain.
Authors
- Jann Hau (ORCID: https://orcid.org/0000-0001-8586-5705)
- Uus Saepuloh (ORCID: https://orcid.org/0000-0003-4742-1091)
- Sela Septima Mariya (ORCID: https://orcid.org/0000-0001-5534-1679)
- Huda Shalahudin Darusman (ORCID: https://orcid.org/0000-0002-2347-0588)
- Lis Rosmanah (ORCID: https://orcid.org/0000-0003-4951-2237)
- Yuliana Yuliana (ORCID: https://orcid.org/0000-0001-5785-2421)
Institutions
- University of Copenhagen (DK)
- IPB University (ID)
- National Research and Innovation Agency (ID)
Publication Details
- Journal
- Open Veterinary Journal
- Published
- 2025-01-01
- DOI
- https://doi.org/10.5455/ovj.2025.v15.i3.7
- Primary Topic
- Bioinformatics and Genomic Networks
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Lembaga Pengelola Dana Pendidikan