<b>Impacts of <i>Pinus pinaster</i> extract and <i>L. carnitine</i> on gene expression and reproductive efficacy against Mancozebinduced testicular toxicity in male rats</b>

The administration of <i>P. pinaster</i> extract and <i>L. carnitine</i>, individually or in combination, has antioxidant effects against mancozeb-induced toxicity via improvement of seminal quality, regeneration of testicular tissues, and upregulation of FSHr and LHr genes positively influence reproductive hormones. This study is the first to demonstrate that the <i>P. pinaster extract</i> plays a therapeutic role in testicular atrophy caused by the fungicide, mancozeb.

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Publication Details

Journal
Open Veterinary Journal
Published
2025-01-01
DOI
https://doi.org/10.5455/ovj.2025.v15.i3.9
Primary Topic
Pesticide Exposure and Toxicity
Type
article
Field-Weighted Citation Impact
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article

Impacts of Pinus pinaster extract and L. carnitine on gene expression and reproductive efficacy against Mancozebinduced testicular toxicity in male rats

Sura Safi Khafaji, Mohammed Fadhil K Alrubaie
Open Veterinary Journal
Pesticide Exposure and Toxicity
article

Impacts of Pinus pinaster extract and L. carnitine on gene expression and reproductive efficacy against Mancozebinduced testicular toxicity in male rats

Sura Safi Khafaji, Mohammed Fadhil K Alrubaie
article en

Abstract

The administration of <i>P. pinaster</i> extract and <i>L. carnitine</i>, individually or in combination, has antioxidant effects against mancozeb-induced toxicity via improvement of seminal quality, regeneration of testicular tissues, and upregulation of FSHr and LHr genes positively influence reproductive hormones. This study is the first to demonstrate that the <i>P. pinaster extract</i> plays a therapeutic role in testicular atrophy caused by the fungicide, mancozeb.

Open Veterinary JournalVol. 15(0)
Qassim University (SA), Ministry of Higher Education and Scientific Research (IQ)
Openalex Percentile: Top 96%
Pesticide Exposure and Toxicity
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&lt;b&gt;Impacts of &lt;i&gt;Pinus pinaster&lt;/i&gt; extract and &lt;i&gt;L. carnitine&lt;/i&gt; on gene expression and reproductive efficacy against Mancozebinduced testicular toxicity in male rats&lt;/b&gt; — Sura Safi Khafaji, Mohammed Fadhil K Alrubaie · Open Veterinary Journal (2025) | TGRS Research Map | TGRS