Changes in A1C Versus GMI Across Glycemic Categories in Clinical Trials of Type 1 Diabetes

Change in GMI is influenced by the baseline A1C of the participants and it underestimates the true change in A1C. Use of GMI as an endpoint in clinical trials may not reliably capture efficacy of an intervention in T1D trials or real-world studies.

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Publication Details

Journal
The Journal of Clinical Endocrinology & Metabolism
Published
2025-04-01
DOI
https://doi.org/10.1210/clinem/dgaf211
Citations
4
Primary Topic
Diabetes Management and Research
Type
article
Field-Weighted Citation Impact
5.18
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article

Changes in A1C Versus GMI Across Glycemic Categories in Clinical Trials of Type 1 Diabetes

Sebastián E Abad, Eslam Montaser, Viral N. Shah
4 citations
The Journal of Clinical Endocrinology & Metabolism
Diabetes Management and Research
5.18
article

Changes in A1C Versus GMI Across Glycemic Categories in Clinical Trials of Type 1 Diabetes

Sebastián E Abad, Eslam Montaser, Viral N. Shah
article en
4 citations

Abstract

Change in GMI is influenced by the baseline A1C of the participants and it underestimates the true change in A1C. Use of GMI as an endpoint in clinical trials may not reliably capture efficacy of an intervention in T1D trials or real-world studies.

The Journal of Clinical Endocrinology & MetabolismVol. 110(12)
Indiana University School of Medicine, Indiana University – Purdue University Indianapolis (US)
Openalex Percentile: Top 5%
Diabetes Management and Research
5.18
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