The tell-tale hearts: Donor-derived invasive fungal infections among orthotopic heart transplant recipients
Donor-derived invasive fungal infections among solid organ transplant recipients are rare but sometimes devastating events associated with notable morbidity and mortality. Here we describe two donor-derived fungal infections - one <i>Candida parapsilosis</i> complex infection and one <i>Aspergillus fumigatus</i> infection - that occurred among heart transplant recipients at a quaternary care center. Both recipients survived their infections, though with substantial morbidity despite aggressive surgical intervention and antifungal therapy.
Authors
- Jay Krishnan (ORCID: https://orcid.org/0009-0008-6791-4671)
- John R. Perfect (ORCID: https://orcid.org/0000-0002-8742-3676)
- Manuela Carugati (ORCID: https://orcid.org/0000-0002-3187-5905)
- Julia A. Messina (ORCID: https://orcid.org/0000-0001-6411-198X)
- Rachel Miller (ORCID: https://orcid.org/0000-0001-7387-1171)
- Cameron R. Wolfe (ORCID: https://orcid.org/0000-0002-5365-5030)
Institutions
- Duke University (US)
- Duke Medical Center (US)
Publication Details
- Journal
- Medical Mycology Case Reports
- Published
- 2025-04-02
- DOI
- https://doi.org/10.1016/j.mmcr.2025.100702
- Citations
- 2
- Primary Topic
- Antifungal resistance and susceptibility
- Type
- article
- Field-Weighted Citation Impact
- 2.79