Whole-cell catalytic production of ethylene glycol from C1 compounds using engineered glycolaldehyde synthase
We report a GALS variant with catalytic efficiency increased by 15.9 times. 0.79 g L −1 ethylene glycol can be synthesized by using it in whole cell biotransformation of C1 compounds.
Authors
- Yin Jia (ORCID: https://orcid.org/0000-0001-6496-6507)
- Chaofeng Shao (ORCID: https://orcid.org/0000-0001-6374-9965)
- Jianyu Long (ORCID: https://orcid.org/0000-0002-5173-1159)
- Tianwei Tan
- Xinyu Tian (ORCID: https://orcid.org/0000-0002-6933-8021)
- Biqiang Chen (ORCID: https://orcid.org/0000-0003-1701-070X)
- Miaomiao Zhou (ORCID: https://orcid.org/0000-0002-5609-2341)
Institutions
- Beijing University of Chemical Technology (CN)
Publication Details
- Journal
- Catalysis Science & Technology
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d4cy01522c
- Citations
- 3
- Primary Topic
- Microbial Metabolic Engineering and Bioproduction
- Type
- article
- Field-Weighted Citation Impact
- 2.42
Funders
- National Natural Science Foundation of China
- National Key Research and Development Program of China