Optical genome mapping with whole genome sequencing identifies complex chromosomal structural variations in acute leukemia
OGM is a fundamental tool that complements G-banding analysis in identifying complex SVs in leukemia samples, and WGS effectively closes the gaps in OGM mapping.
Authors
- Yin‐Hsiu Chien (ORCID: https://orcid.org/0000-0001-8802-5728)
- Meng-Ju Melody Tsai
- Yung‐Li Yang (ORCID: https://orcid.org/0000-0002-3598-7218)
- Pui–Yan Kwok (ORCID: https://orcid.org/0000-0002-5087-3059)
- Hsiao‐Huei Chen (ORCID: https://orcid.org/0000-0003-2914-6057)
- Chih‐Hsiang Yu
- Wuh‐Liang Hwu (ORCID: https://orcid.org/0000-0001-6690-4879)
- Ni‐Chung Lee (ORCID: https://orcid.org/0000-0002-5011-7499)
- Hsiao‐Jung Kao (ORCID: https://orcid.org/0009-0008-1106-3898)
Institutions
- National Taiwan University (TW)
- University of California, San Francisco (US)
- China Medical University (TW)
- Institute of Biomedical Sciences, Academia Sinica (TW)
- Institute of Human Genetics (PL)
- China Medical University Hospital (TW)
- National Taiwan University Hospital (TW)
- Institute of Statistical Science, Academia Sinica (TW)
- National Yunlin University of Science and Technology (TW)
Publication Details
- Journal
- Frontiers in Genetics
- Published
- 2025-04-02
- DOI
- https://doi.org/10.3389/fgene.2025.1496847
- Citations
- 3
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 2.81
Funders
- National Taiwan University Hospital