Plasma methylated HIST1H3G as a non-invasive biomarker for diagnostic modeling of hepatocellular carcinoma
Together, we identified and validated a diagnostic model that incorporated methylated <i>HIST1H3G</i> and clinically applicable serological indicators in HCC. The findings of our study established a pivotal foundation for the development of a non-invasive approach to identification and management in HCC.
Authors
- Yingchun Cai (ORCID: https://orcid.org/0000-0002-8600-7275)
- Weiwei Zhu (ORCID: https://orcid.org/0000-0002-9969-2232)
- Zujiang Yu (ORCID: https://orcid.org/0000-0003-0954-5472)
- Jun Lei (ORCID: https://orcid.org/0000-0001-5104-3738)
- Jia Yu (ORCID: https://orcid.org/0000-0002-4481-2022)
- Huifen Wang (ORCID: https://orcid.org/0000-0001-9699-342X)
- Ang Li (ORCID: https://orcid.org/0000-0002-9802-9359)
Institutions
- First Affiliated Hospital of Zhengzhou University (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-04-02
- DOI
- https://doi.org/10.3389/fmed.2025.1571737
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Zhengzhou University
- First Affiliated Hospital of Zhengzhou University