Adult Height, Cardiovascular Disease, and the Underlying Mechanism: A Comprehensive Epidemiological and Genetic Analysis
Our study confirms the health effects of height on CAD, atrial fibrillation, and venous thromboembolism and emphasizes forced vital capacity as the primary pathway that links height to CAD. Importantly, it indicates that the CAD risk associated with nonmodifiable height could be mitigated through enhanced lung function and cardiometabolic conditions.
Authors
- Xunying Zhao (ORCID: https://orcid.org/0000-0002-6754-9773)
- Yunjie Liu (ORCID: https://orcid.org/0000-0001-9454-5666)
- Xueyao Wu (ORCID: https://orcid.org/0000-0001-6856-0520)
- Hai Yang (ORCID: https://orcid.org/0000-0001-5210-8468)
- Peijing Yan (ORCID: https://orcid.org/0000-0001-5525-2465)
- Yuqin Yao (ORCID: https://orcid.org/0000-0003-2097-6978)
- Tianpei Ma (ORCID: https://orcid.org/0000-0002-4510-9697)
- Chunxia Yang (ORCID: https://orcid.org/0000-0002-5566-3990)
- Huijie Cui (ORCID: https://orcid.org/0000-0003-1289-3179)
- Rong Xiang (ORCID: https://orcid.org/0000-0002-6588-2724)
- Yanqiu Zou
- Hao Yu (ORCID: https://orcid.org/0000-0003-3855-4722)
- Li Zhang (ORCID: https://orcid.org/0000-0002-1617-5943)
- Ling Zhang (ORCID: https://orcid.org/0000-0002-8343-2719)
- Yutong Wang (ORCID: https://orcid.org/0000-0001-7796-7779)
- Wenqiang Zhang (ORCID: https://orcid.org/0000-0002-0317-3914)
- Ben Zhang (ORCID: https://orcid.org/0000-0002-4972-5171)
- Xia Jiang
- Jinyu Xiao (ORCID: https://orcid.org/0000-0003-2318-313X)
- Zhenmi Liu (ORCID: https://orcid.org/0000-0003-0840-1071)
- Jiayuan Li (ORCID: https://orcid.org/0000-0002-2920-1637)
- Mingshuang Tang
- Bin Xu
- Lin Chen (ORCID: https://orcid.org/0009-0003-6995-8137)
- Yang Qu
Institutions
- Sichuan University (CN)
- West China Medical Center of Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
- Hainan Medical University (CN)
Publication Details
- Journal
- Canadian Journal of Cardiology
- Published
- 2025-04-02
- DOI
- https://doi.org/10.1016/j.cjca.2025.03.027
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00