Cross one single body 49 tissues single-cell transcriptome reveals detailed macrophage heterogeneity during pig pregnancy

We constructed a multiple-tissue single-cell transcriptome atlas of macrophages in one single healthy pregnant pig, revealing their molecular differences and commonalities across tissues and species. Our study provides a valuable resource for understanding macrophage diversity and tissue-specific macrophage adaptations during pregnancy in pigs.

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Publication Details

Journal
Frontiers in Immunology
Published
2025-04-02
DOI
https://doi.org/10.3389/fimmu.2025.1574120
Citations
3
Primary Topic
IL-33, ST2, and ILC Pathways
Type
article
Field-Weighted Citation Impact
2.39

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article

Cross one single body 49 tissues single-cell transcriptome reveals detailed macrophage heterogeneity during pig pregnancy

Liping Cai, Lusheng Huang, Chih‐Huang Lai, Xiaoyun Chen
3 citations
Frontiers in Immunology
IL-33, ST2, and ILC Pathways
2.39
article

Cross one single body 49 tissues single-cell transcriptome reveals detailed macrophage heterogeneity during pig pregnancy

Liping Cai, Lusheng Huang, Chih‐Huang Lai, Xiaoyun Chen
article en
3 citations

Abstract

We constructed a multiple-tissue single-cell transcriptome atlas of macrophages in one single healthy pregnant pig, revealing their molecular differences and commonalities across tissues and species. Our study provides a valuable resource for understanding macrophage diversity and tissue-specific macrophage adaptations during pregnancy in pigs.

Frontiers in ImmunologyVol. 16
Jiangxi Agricultural University (CN)
National Natural Science Foundation of China
Openalex Percentile: Top 12%
IL-33, ST2, and ILC Pathways
2.39
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