Pregnancy outcomes of 4,200 fetuses with increased nuchal translucency in Henan, China
The incidence of increased NT in our study was 0.49%, which was associated with chromosomal abnormalities and developmental disorders, leading to an increased risk of adverse pregnancy outcomes. Abnormal ultrasound soft markers, along with NT > 4 mm, may further elevate the risk of adverse pregnancy outcomes. These findings should be taken seriously in the context of further prenatal diagnosis for fetuses with increased NT.
Authors
- Wenke Yang (ORCID: https://orcid.org/0000-0002-6723-3998)
- Ruili Wang (ORCID: https://orcid.org/0000-0001-7164-2332)
- Qiongrui Zhao
- Zhenglong Guo (ORCID: https://orcid.org/0000-0002-6251-3093)
- Shixiu Liao (ORCID: https://orcid.org/0000-0003-3126-0027)
- Yuwei Zhang (ORCID: https://orcid.org/0000-0001-8927-3184)
- Xin Wang (ORCID: https://orcid.org/0000-0001-9325-3194)
- Jinming Wang (ORCID: https://orcid.org/0000-0001-7628-2022)
- Bingtao Hao (ORCID: https://orcid.org/0000-0003-1997-9338)
Institutions
- Henan Provincial People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-04-02
- DOI
- https://doi.org/10.3389/fmed.2025.1514504
- Citations
- 1
- Primary Topic
- Prenatal Screening and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 3.49
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Henan Province
- National Health Commission of the People's Republic of China