lncRNA Ubr5 promotes BMSCs apoptosis and inhibits their proliferation and osteogenic differentiation in weightless bone loss
This study revealed the molecular pathogenesis of weightless bone loss, identified lncRNA Ubr5 as a potential intervention target, and provided an important scientific basis and strategic guidance for the prevention and treatment of weightless bone loss.
Authors
- Yingjun Tan
- Jiaxiang Li (ORCID: https://orcid.org/0000-0002-8769-0440)
- Yongchun Wang (ORCID: https://orcid.org/0000-0002-8297-2908)
- Xingcheng Zhao (ORCID: https://orcid.org/0000-0002-8899-7196)
- Yuan Gao (ORCID: https://orcid.org/0000-0002-0628-4484)
- Na Li (ORCID: https://orcid.org/0000-0001-5229-2787)
- Dong Wang (ORCID: https://orcid.org/0000-0002-8340-2763)
- Xi Li (ORCID: https://orcid.org/0000-0001-6325-3230)
- Ming Yan (ORCID: https://orcid.org/0000-0003-0669-1087)
- Yikai Pan (ORCID: https://orcid.org/0000-0002-4875-7921)
Institutions
- Air Force Engineering University (CN)
- Xijing Hospital (CN)
- China Astronaut Research and Training Center (CN)
- Air Force Medical University (CN)
Publication Details
- Journal
- Frontiers in Cell and Developmental Biology
- Published
- 2025-04-02
- DOI
- https://doi.org/10.3389/fcell.2025.1543929
- Citations
- 1
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.94