Antioxidant, Antimicrobial, and Potential Biomedical Applications of Green Synthesized Silver Nanoparticles Using Aloe barbadensis Root

The present study focuses on the green synthesis and physicochemical characterization of silver nanoparticles (AgNPs) using Aloe barbadensis root extract. The green synthesized AgNPs were characterized using X-ray diffraction (XRD), UV-visible spectrophotometry, Fourier-transform infrared spectroscopy (FTIR), dynamic light scattering (DLS), and scanning electron microscopy (SEM). The characteristic UV absorption peak at 328 nm confirmed the successful synthesis of AgNPs. The antioxidant activity of AgNPs was assessed through DPPH and hydrogen peroxide scavenging assays, with maximum free radical scavenging activities of 75.5 % and 73%, respectively, at 500 ug/mL. Antimicrobial activity of the AgNPs was demonstrated against both Gram-positive and Gram-negative bacteria, with a maximum zone of inhibition of 22 mm. Additionally, the synthesized AgNPs displayed potential biomedical applications. These findings highlight the potential of Aloe barbadensis root-mediated AgNPs for therapeutic, antimicrobial, and antioxidative applications, underscoring their relevance in sustainable nanotechnology and biomedicine.