Synthesis, Characterization & Biological Activity Assessment of a New Oxadiazole Derivative Based on Nicotinic Hydrazide and Using It for Extraction of Ni and Co from Aqueous Solutions

In a recent study, a novel chemical generated from 1,3,4-oxadiazole was synthesized by mixing transition metals with nicotinic hydrazide using their water-dissolved chloride salts. To determine the chemical properties of the bonds and their chains, H1-NMR, FT-IR, and mass spectrometry(MS) methods were used. In addition, conduction sensitivity measurements were performed. The size of the inhibitory zone for Candida Kruse, Candida albicans, Pseudomonas aeruginosa, and Staphylococcus aureus, was assessed after generated complexe was tested against bacteria by means of the diffusion method. The Hyper Chem program was used to do theoretical calculations utilizing the MP3 approach in order to examine the stability energy of compounds and pinpoint the precise sites where they form complexes with metal elements.