The Placebo Hypoalgesic Response Is Reduced in Healthy Older Adults Showing a Decline in Executive Functioning
We demonstrated an age-related reduction in placebo hypoalgesia in older adults showing a decline in executive functioning. This is an important finding, considering the fact that placebo effects contribute to positive treatment outcomes. Our results advocate the assessment of executive functions when investigating the influence of aging on placebo effects, as variable aging trajectories of decline may influence overall group comparisons.
Authors
- Fernand Anton (ORCID: https://orcid.org/0000-0001-9570-7620)
- Marian van der Meulen (ORCID: https://orcid.org/0000-0003-4191-4952)
- Pedro Montoya (ORCID: https://orcid.org/0000-0001-8652-948X)
- Angelika M. Dierolf (ORCID: https://orcid.org/0000-0003-0644-2208)
- Ana María González‐Roldán
- Katharina Miriam Rischer (ORCID: https://orcid.org/0000-0003-3509-9760)
Institutions
- University of Luxembourg (LU)
- Health Research Institute of the Balearic Islands (ES)
- Research Institute of Health Sciences (ES)
- Universitat de les Illes Balears (ES)
Publication Details
- Journal
- Journal of Pain Research
- Published
- 2025-04-01
- DOI
- https://doi.org/10.2147/jpr.s488198
- Primary Topic
- Pain Management and Placebo Effect
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Fonds National de la Recherche Luxembourg