Comprehensive validation of a custom three-point bending system for standardized diabetic fracture models in rats
Our validated three-point bending system significantly enhances reproducibility, consistency, and methodological rigor in animal fracture research. This standardized model provides an ideal foundation for future preclinical studies investigating diabetic fracture healing mechanisms and potential therapeutic interventions.
Authors
- Zheng Guo (ORCID: https://orcid.org/0000-0002-2294-3873)
- Weijie Wang (ORCID: https://orcid.org/0000-0003-3987-9270)
- Qidong Guo
Institutions
- Shanxi Medical University (CN)
- University of Dundee (GB)
- Second Hospital of Shanxi Medical University (CN)
Publication Details
- Journal
- Journal of Orthopaedic Surgery and Research
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1186/s13018-025-05754-8
- Primary Topic
- Bone health and osteoporosis research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China