Polyethylenimine-Conjugated Au-NPs as an Efficient Vehicle for in vitro and in vivo DNA Vaccine Delivery
PEI-coated Au-NPs demonstrate exceptional potential as non-toxic, high-efficiency carriers for DNA vaccines, enabling robust humoral and cellular immune responses. This strategy holds promises for advancing gene therapy and combating rapidly evolving pathogens like HuNoV, with broader applications in targeted drug delivery.
Authors
- Aras Kartouzian (ORCID: https://orcid.org/0000-0002-2193-2902)
- Kamyar Shameli (ORCID: https://orcid.org/0000-0002-3955-4604)
- Hassan Moeini
- Alexandra Heiz (ORCID: https://orcid.org/0009-0005-1189-4841)
Institutions
- Fraunhofer Institute for Interfacial Engineering and Biotechnology (DE)
- Technical University of Munich (DE)
Publication Details
- Journal
- International Journal of Nanomedicine
- Published
- 2025-04-01
- DOI
- https://doi.org/10.2147/ijn.s493211
- Citations
- 3
- Primary Topic
- RNA Interference and Gene Delivery
- Type
- article
- Field-Weighted Citation Impact
- 2.42
Funders
- Deutsche Forschungsgemeinschaft
- Technische Universität München