Anxiety disorders in patients with thyroid nodules vs. thyroid cancer: a retrospective cohort study

This study identifies a significant association between thyroid nodules and increased anxiety risk, while risks for depression, mood disorders, and insomnia were lower compared to thyroid cancer patients. Furthermore, a sensitivity analysis compared thyroid nodule patients to the general population and revealed elevated anxiety risk in patients with nodules, reinforcing that this increased risk is not solely attributable to cancer-related factors. Further research is warranted to confirm these findings and explore mechanisms underlying the psychological impact of thyroid nodules.