Pharmacokinetic boosting of olaparib: Study protocol of a multicentre, open-label, randomised, non-inferiority trial (PROACTIVE-B)

The PROACTIVE study has been published at ClinicalTrials.gov under NCT05078671 on October 14, 2021 and at EudraCT under 2021-004032-28 on August 24, 2021.

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Publication Details

Journal
Contemporary Clinical Trials Communications
Published
2025-04-01
DOI
https://doi.org/10.1016/j.conctc.2025.101477
Citations
2
Primary Topic
PARP inhibition in cancer therapy
Type
article
Field-Weighted Citation Impact
2.09

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article

Pharmacokinetic boosting of olaparib: Study protocol of a multicentre, open-label, randomised, non-inferiority trial (PROACTIVE-B)

Alwin D. R. Huitema, Frans L. Opdam, Rob ter Heine, Ingrid A Boere et al.
2 citations
Contemporary Clinical Trials Communications
PARP inhibition in cancer therapy
2.09
article

Pharmacokinetic boosting of olaparib: Study protocol of a multicentre, open-label, randomised, non-inferiority trial (PROACTIVE-B)

Alwin D. R. Huitema, Frans L. Opdam, Rob ter Heine, Ingrid A Boere, Marjolijn J. L. Ligtenberg, Nielka P. van Erp, Wietske Kievit, Gabe S. Sonke, Niels A.D. Guchelaar, Joanneke K. Overbeek, Petronella B. Ottevanger, Haiko J. Bloemendal, Stijn L.W. Koolen, Ron H.J. Mathijssen, Ma Ida Mohmaed Ali, Muriëlle Sark, Carolien Hovenier
article en
2 citations

Abstract

The PROACTIVE study has been published at ClinicalTrials.gov under NCT05078671 on October 14, 2021 and at EudraCT under 2021-004032-28 on August 24, 2021.

Contemporary Clinical Trials CommunicationsVol. 45
Radboud University Nijmegen (NL), Utrecht University (NL), Erasmus MC (NL), Radboud University Medical Center (NL), The Netherlands Cancer Institute (NL), University Medical Center Utrecht (NL), Borstkankervereniging Nederland (NL), Oncode Institute (NL), Florence (Netherlands) (NL), Princess Máxima Center (NL), Erasmus MC Cancer Institute (NL)
Amgen, ZonMw, Nederlandse Federatie van Universitair Medische Centra
Gender equality
Openalex Percentile: Top 13%
PARP inhibition in cancer therapy
2.09
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