Growth associated protein 43 (GAP-43) predicts brain amyloidosis in Alzheimer’s dementia continuum: an [18 F] AV-45 study
This study provides evidence supporting the role of GAP-43 as a potential biomarker for AD, particularly in relation to predicting the amyloid pathology pattern in the brain in the MCI stage.
Authors
- Mahsa Mayeli (ORCID: https://orcid.org/0000-0003-4656-156X)
- Saeed Mardani (ORCID: https://orcid.org/0000-0002-4798-1809)
- Mohammad Sadeghi (ORCID: https://orcid.org/0000-0003-0351-7876)
- Reza Nemati (ORCID: https://orcid.org/0000-0001-8155-8855)
- Alireza Abadi (ORCID: https://orcid.org/0000-0002-7433-261X)
- Yassin Rahnama (ORCID: https://orcid.org/0009-0004-1133-1734)
- Niloofar Khoshroo
- Parsa Saberian (ORCID: https://orcid.org/0000-0002-8889-8630)
- Atefeh Heydari (ORCID: https://orcid.org/0009-0001-2545-4055)
- Hamide Nasiri (ORCID: https://orcid.org/0009-0008-2361-3308)
- Ahmadreza Sohrabi-Ashlaghi
- Ali Yaghoobpoor
Institutions
- Zanjan University of Medical Sciences (IR)
- Mashhad University of Medical Sciences (IR)
- Shiraz University of Medical Sciences (IR)
- University of Tehran (IR)
- Islamic Azad University Medical Branch of Tehran (IR)
- Islamic Azad University, Arak (IR)
- Urmia University (IR)
- Islamic Azad University, Shahr-e-Qods Branch (IR)
- Hormozgan University of Medical Sciences (IR)
- Urmia University of Medical Sciences (IR)
- Tehran University of Medical Sciences (IR)
Publication Details
- Journal
- BMC Neurology
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1186/s12883-025-04140-5
- Citations
- 2
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.33
Funders
- Foundation for the National Institutes of Health
- Alzheimer's Association
- Bristol-Myers Squibb
- Eli Lilly and Company
- Pfizer
- Biogen
- Meso Scale Diagnostics
- Alzheimer's Disease Neuroimaging Initiative
- BioClinica
- Novartis Pharmaceuticals Corporation
- Northern California Institute for Research and Education
- Eisai
- Servier
- H. Lundbeck A/S
- IXICO
- National Institutes of Health
- Genentech
- Canadian Institutes of Health Research