Features of the Alcohol Dependence Complicated by Epileptic Seizures

A naturalistic observational comparative study was conducted on two groups of patients: 105 individuals with alcohol dependence complicated by epileptic seizures and 83 individuals with alcohol dependence without epileptic seizures. It was shown that the studied patient population had a more severe course of the disease, which was manifested in a predominance of high disease progression, continuous drinking patterns, frequent repeated hospitalizations, and frequent complications of withdrawal syndrome in the form of delirium tremens. Binary analysis revealed a close relationship between biological and environmental factors. In the presence of aggravating biological factors, the course of the disease worsens, it develops at an earlier age, has high progression, and is associated with an increased frequency of traumatic brain injuries (TBI) as well as a higher incidence and frequency of psychoses.