Dynamic risk stratification and treatment optimization in sepsis: the role of NLPR
NLPR is a simple, accessible, and robust biomarker for sepsis risk stratification, integrating inflammation and coagulation data. It complements traditional scoring systems, provides actionable thresholds for early intervention, and facilitates dynamic monitoring. These findings underscore NLPR's potential to improve clinical decision-making and outcomes in sepsis management, warranting validation in prospective multicenter studies.
Authors
- Lili Dai (ORCID: https://orcid.org/0000-0003-4886-9138)
- Hongxia Niu (ORCID: https://orcid.org/0000-0001-5367-3813)
- Ming Zhang (ORCID: https://orcid.org/0000-0002-6027-4594)
- Qiqi Chen
- Yuxin Xia (ORCID: https://orcid.org/0000-0003-3211-2579)
- Ya Deng
- Yanna Yang
Institutions
- North China Electric Power University (CN)
- State Grid Corporation of China (China) (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-04-02
- DOI
- https://doi.org/10.3389/fphar.2025.1572677
- Citations
- 6
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 8.13