Glycosyl terpenoid-rich fraction of TeMac™ attenuates oxidative stress, inhibits cholinesterases enzyme activities, and protects brain against scopolamine-induced histopathological alterations in rats
These findings suggest that the active ingredients in GT-TeMac™ are promising drug candidates for the treatment of cognitive disorders associated with oxidative stress in AD.
Authors
- Damaris Enyegue Mandob
- Martin Fonkoua (ORCID: https://orcid.org/0000-0001-7800-9564)
- Judith Laure Ngondi (ORCID: https://orcid.org/0000-0002-4625-6111)
- Bruno Dupon Akamba Ambamba (ORCID: https://orcid.org/0009-0004-3747-6624)
- Fils Armand Ella
- Ghislain Djiokeng Paka
- Mbah Ntepe Leonel Javeres (ORCID: https://orcid.org/0000-0002-2273-2697)
- Guy Roussel Takuissu
- Quentin Cicilien Piebeng Nongni
Institutions
- Université de Yaoundé I (CM)
- Ministry of Scientific Research and Innovation (CM)
Publication Details
- Journal
- Biomedicine & Pharmacotherapy
- Published
- 2025-04-02
- DOI
- https://doi.org/10.1016/j.biopha.2025.118010
- Primary Topic
- Phytochemistry and Biological Activities
- Type
- article
- Field-Weighted Citation Impact
- 0.00