Mucinous, Tubular and Spindle Cell Carcinoma of the Kidney: a Case Report and Literature Review

INTRODUCTION: Mucinous, tubular and spindle cell renal carcinoma is an epithelial neoplasm which makes up less than 1% of all renal neoplasms. It is most common in the renal cortex and is characterized by tubules which merge with soft spindle cells in a myxoid stroma. Usually, it is an asymptomatic tumor diagnosed incidentally in imaging exams. CASE DESCRIPTION: A 67-year-old male patient was attended at a university hospital with diffuse abdominal pain. A computed tomography scan showed a renal mass of approximately 9 cm in its largest dimension. He underwent a nephrectomy, and the histopathological analysis was compatible with mucinous, tubular and spindle cell renal carcinoma. CONCLUSION: Mucinous tubular and spindle cell carcinoma is a rare neoplasm, with nonspecific findings and, therefore, of a difficult diagnosis. The absence of a spindle component and genetic analysis may help in differential diagnosis, essential to determining the correct prognosis and patient follow-up.

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Recet
Published
2025-04-01
DOI
https://doi.org/10.55825/recet.sbu.0266
Primary Topic
Renal cell carcinoma treatment
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article
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article

Mucinous, Tubular and Spindle Cell Carcinoma of the Kidney: a Case Report and Literature Review

Gianpaolo Basso, Paulo Eduardo Dietrich Jaworski, Samya Hamad Mehanna, Mariana Sestrem Tortoza Bignelli et al.
Recet
Renal cell carcinoma treatment
article

Mucinous, Tubular and Spindle Cell Carcinoma of the Kidney: a Case Report and Literature Review

Gianpaolo Basso, Paulo Eduardo Dietrich Jaworski, Samya Hamad Mehanna, Mariana Sestrem Tortoza Bignelli, Alexandre Favretto Pastorello
article en

Abstract

INTRODUCTION: Mucinous, tubular and spindle cell renal carcinoma is an epithelial neoplasm which makes up less than 1% of all renal neoplasms. It is most common in the renal cortex and is characterized by tubules which merge with soft spindle cells in a myxoid stroma. Usually, it is an asymptomatic tumor diagnosed incidentally in imaging exams. CASE DESCRIPTION: A 67-year-old male patient was attended at a university hospital with diffuse abdominal pain. A computed tomography scan showed a renal mass of approximately 9 cm in its largest dimension. He underwent a nephrectomy, and the histopathological analysis was compatible with mucinous, tubular and spindle cell renal carcinoma. CONCLUSION: Mucinous tubular and spindle cell carcinoma is a rare neoplasm, with nonspecific findings and, therefore, of a difficult diagnosis. The absence of a spindle component and genetic analysis may help in differential diagnosis, essential to determining the correct prognosis and patient follow-up.

RecetVol. 12(2)
Hospital Universitário Evangélico de Curitiba (BR), Faculdade Evangélica do Paraná (BR)
Openalex Percentile: Top 90%
Renal cell carcinoma treatment
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