Alterations in HMGB1, ROS1, FGFR1, FGFR2, IL6, and TLR4 are associated with worse survival in patients with esophageal squamous cell carcinoma
This study highlights that genomic alterations in these six genes are associated with poorer OS in ESCC, despite higher TMB potentially increasing tumor neo-antigens. These findings underscore the need for further research to explore their prognostic and therapeutic potential.
Authors
- Victor C. Kok (ORCID: https://orcid.org/0000-0003-3440-8154)
- Ming-Chih Wang
- Chien-Kuan Lee
- Yen-Te Lu
Institutions
- Kuang Tien General Hospital (TW)
Publication Details
- Journal
- Współczesna Onkologia
- Published
- 2025-01-01
- DOI
- https://doi.org/10.5114/wo.2025.149138
- Primary Topic
- Esophageal Cancer Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00