Efficacy and safety of care bundles in the treatment of delirium in ICU patients: a meta-analysis and systemic review

Care bundles have positive effects on delirium in ICU patients. However, results with significant heterogeneity should be interpreted with caution, and differences in bundles need to be taken into account. More multi-center, largesample randomized controlled studies are required to further explore the optimal components and combinations of care bundles.