Germline variants analysis of Chinese breast cancer patients reveals numerous alterations in homologous recombination genes

HR-gene testing in breast cancer could help to find new suspected pathogenic variants and increase the clinical benefit of multi-gene testing for breast cancer.

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Publication Details

Journal
Future Science OA
Published
2025-04-01
DOI
https://doi.org/10.1080/20565623.2025.2458432
Primary Topic
PARP inhibition in cancer therapy
Type
article
Field-Weighted Citation Impact
0.00

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article

Germline variants analysis of Chinese breast cancer patients reveals numerous alterations in homologous recombination genes

Zhaoyun Jiang, Bing Xu, Bo Sun, Beibei Yang et al.
Future Science OA
PARP inhibition in cancer therapy
article

Germline variants analysis of Chinese breast cancer patients reveals numerous alterations in homologous recombination genes

Zhaoyun Jiang, Bing Xu, Bo Sun, Beibei Yang, Su Lu, Mengjian Li, Qixi Wu, Juan Zhang, Liqiang Qi
article en

Abstract

HR-gene testing in breast cancer could help to find new suspected pathogenic variants and increase the clinical benefit of multi-gene testing for breast cancer.

Future Science OAVol. 11(1)
Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Cancer Institute (WIA) (IN), Tianjin Medical University Cancer Institute and Hospital (CN)
National Natural Science Foundation of China
Good health and well-being
Openalex Percentile: Top 91%
PARP inhibition in cancer therapy
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Germline variants analysis of Chinese breast cancer patients reveals numerous alterations in homologous recombination genes — Zhaoyun Jiang, Bing Xu, et al. · Future Science OA (2025) | TGRS Research Map | TGRS