Platelet rich fibrin and commercial sealants for dural closure in neurosurgery: An in vitro study
Autologous platelet-rich fibrin in a two-step procedure displayed enhanced augmentation and reinforced watertight closure of the dura mater, exhibiting a four-fold increase in leak pressure compared to standard running suture alone. Among other commonly utilized commercial sealants, it ranked second with demonstrated consistency in its performance.
Authors
- Jürgen Beck (ORCID: https://orcid.org/0000-0002-4160-7760)
- Juergen Grauvogel (ORCID: https://orcid.org/0000-0003-3330-3860)
- Angeliki Stathi (ORCID: https://orcid.org/0000-0002-9820-6570)
- Kevin Joseph (ORCID: https://orcid.org/0000-0001-6317-8736)
- Amir El Rahal (ORCID: https://orcid.org/0000-0002-8250-5883)
- Katerina Argiti (ORCID: https://orcid.org/0000-0003-3853-4094)
- Florian Volz (ORCID: https://orcid.org/0000-0001-7274-519X)
- Ioannis Vasilikos (ORCID: https://orcid.org/0000-0001-5820-1110)
- Daniel Strahnen (ORCID: https://orcid.org/0009-0001-1903-2729)
- Mukesch Johannes Shah (ORCID: https://orcid.org/0000-0002-7224-9185)
- Vidhya Madapusi Ravi (ORCID: https://orcid.org/0000-0003-0062-2099)
- Ulrich Hubbe
- Roland Rölz
Institutions
- University of Freiburg (DE)
- University Medical Center Freiburg (DE)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1371/journal.pone.0319349
- Citations
- 3
- Primary Topic
- Head and Neck Surgical Oncology
- Type
- article
- Field-Weighted Citation Impact
- 6.02