Secretion of cochlin-tomoprotein (LCCL) in the middle ear following acute tympanic injury: implications for perilymph fistula diagnosis
Tympanostomy for the CTP test results in a false positive when the sampling is delayed. While LCCL is a reliable biomarker for clinically detecting perilymph fistula, the timing of its application should be carefully considered to avoid false-positive results.
Authors
- Han Matsuda (ORCID: https://orcid.org/0009-0002-7503-0872)
- Jinsei Jung (ORCID: https://orcid.org/0000-0003-1906-6969)
- Seong Hoon Bae (ORCID: https://orcid.org/0000-0001-9243-9392)
- Tetsuo Ikezono (ORCID: https://orcid.org/0000-0002-6929-5084)
- Hyoyeol Kim
- Haeng Ran Park
- Yukihide Maeda (ORCID: https://orcid.org/0000-0002-8106-9055)
- Tomohiro Matsumura
- Shiho Saito
Institutions
- Yonsei University (KR)
- Gangnam Severance Hospital (KR)
- Nippon Medical School (JP)
- Saitama Medical University (JP)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2025-04-02
- DOI
- https://doi.org/10.3389/fneur.2025.1527311
- Citations
- 2
- Primary Topic
- Vestibular and auditory disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.68