Simulation study on the force-electric effect of piezoelectric bone and osteocytes under static and dynamic compression

This study analyzed the generation rule of streaming potential (SP) considering the piezoelectric effect of bone under static and dynamic compression. The piezoelectric equation was introduced into the equation of SP, and an osteon's 3D fluid-structure interaction finite element model with osteocytes was developed using COMSOL software. Seven working conditions helped study SP. The results showed positive and negative SP alternately acted on osteocyte under dynamic loads, and SP was about three orders of magnitude higher than that under static loads. Therefore, dynamic loads improved the osteocytes' force-electric microenvironment. The force-electric effect revealed the mechanism of treatment of osteoporosis.